Erythromycin hmoov CAS 114-07-8

Erythromycin A yog ib tug 14-membered macrocyclic lactone nrog broad spectrum tshuaj tua kab mob, cais los ntawm Saccharopolyspora erythraea (yav tas los Streptomyces erythreus) nyob rau hauv 1952. Erythromycin yog ib qho ntawm tsuas yog ib tug puv tes ntawm microbial metabolites ntawm cov kab mob metabolites rau kev kho mob. 50 xyoo dhau los. Erythromycin tau ua rau cov tiam tshiab ntawm semi-synthetic derivatives nrog txhim kho stability thiab potency. Peb cov khoom tau raug HPLC-purified kom tshem tawm cov kab mob thiab cov khoom degradation.

Siv rau hauv kev kho mob ntawm cov kab mob tshwm sim los ntawm cov kab mob ntawm cov kab mob nyob rau hauv cov kab mob hauv qab no: kab mob ua pa (sab sauv thiab qis) ntawm me me mus rau theem nrab, pertussis ( hnoos hawb pob), raws li txuas rau cov tshuaj tua kab mob hauv cov kab mob.
 

Cov ntawv sau npe Erythromycin, npaj rau siv los ua tus qauv sab hauv rau kev ntsuas Erythromycin los ntawm GC- lossis LC-mass spectrometry.

1. Erythromycin tuaj yeem cuam tshuam cov protein synthesis ntawm cov kab mob, qhov dav dav tiv thaiv kab mob gram zoo, feem ntau yog siv rau kev kho mob ntawm G los ntawm penicillin resistant Staphylococcus aureus kab mob.

2. Erythromycin yog tshuaj tua kab mob macrolide uas nquag siv, tshuaj tua kab mob zoo sib xws nrog penicillin, feem ntau yog siv rau cov neeg mob ua xua rau penicillin, los yog penicillin resistant Staphylococcus aureus kab mob, kuj siv tau rau Streptococcus, pneumococcus kab mob thiab kab mob diphtheria.

3. Qhov no yog lub nplhaib loj lactone chav kawm tshuaj tua kab mob derivatives intermediates ntawm bacteriostatic tshuaj tua kab mob, tshuaj tua kab mob spectrum zoo ib yam li cov kab mob ntsuab.

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